We optimized the amount of lipid supplement needed for each clone. The titer increase over control was 20% for clone 1 in SAFC media, 25% for clone 2 in FortiCHO media, and 50% for clone 3 in OptiCHO media. Those increases came across three different Cell-Ess concentration ranges. We found an increased yield regardless of starting titers (which were 540 mg/L for clone 1, 125 mg/L for clone 2, and 3.2 g/L for clone 3). The increase in titer also occurred with three different base serum-free media systems and at three different locations.
Cell-Ess is proven yet again